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Boutique hotels are what the latest travelers are after. They offer unique experiences with an immersive design that are Instagrammable from any angle. I’ve rounded up the best-designed boutique hotels as well as Airbnbs throughout the entire country including spots in Panama City, Boquete, Bocas del Toro, and more. From eco-tree house retreats in the jungle, waterfront bungalows, and charming rooms in the historic district, these are the most unique boutique hotels in Panama.

The Firefly | BOOK NOW

Location: Isla Bastimientos, Bocas del Toro

Photo credit: @charlesaydlett

The Firefly is a beautiful rustic retreat on Isla Bastimientos in Bocas del Toro and features a restaurant, bar, pool, yoga studio, and lounge space. This is the type of property down to earth eco-lovers will enjoy as you’re immersed in the beautiful nature. An amazing rotating breakfast will be prepared for you each morning that utilizes fresh, local ingredients. The staff is also able to assist you with booking local tours to explore the other islands of Bocas del Toro.

Nayara | BOOK NOW

Location: Bocas del Toro

If you’re looking for an exclusive, all-inclusive luxury experience in Bocas del Toro, Nayara is unlike anything that has ever existed in the area. You can choose to stay in one of their overwater bungalows or whimsical treehouse cabins where you’ll have a whole island to explore yourself. Amenities include a uniquely designed floating beach, gourmet dining, craft cocktail bar, gym, swimming pool, spa, and the stunning natural landscapes that surround you.

River Treehouse | BOOK NOW

Location: Boquete

If the heat of the jungle isn’t for you, stay at the River Treehouse in the cool mountains of Boquete, Panama. The treehouse is situated next to a soothing river that will lull you to sleep each night and is part of a small nature resort.

Catalina’s Hideaway | BOOK NOW

Location: Lago Bay (Lagartero), Veraguas

Catalina’s Hideaway is an eco-aware beachfront space with great music, food, and flow. The luxurious casitas & treehouse are nestled on 2.5 acres of pristine coastline; where the jungle meets the ocean. It’s on the way to the popular surf and dive town of Santa Catalina but also hidden where travelers can immerse themselves in the undisturbed nature of Panama. The open-air restaurant & bar, “Sobremesa”, highlights a farm-to-table philosophy and features an array of cocktails and snacks for your enjoyment at the beachfront lounge or infinity pool.

Sol Bungalows | BOOK NOW

Location: Isla Solarte, Bocas del Toro

Sol Bungalows offers an affordable & luxurious overwater bungalow experience on Isla Solarte in Bocas del Toro. The bungalows have glass floors, thatched roofs, deck hammocks, direct water access, and snorkeling right in front, among many other great amenities. 

La Coralina Island House | BOOK NOW

Location: Bocas del Toro

La Coralina Island House brings the Bali-vibes to Bocas. The architecture blends perfectly into the surrounding nature while maintaining luxury standards that will satisfy any traveler. The hotel is right on the beach with a beautiful swimming pool, wellness spa, and fabulous restaurant.

Amarla | BOOK NOW

Location: Casco Viejo, Panama City

Amarla has created a beautiful boutique hotel in the heart of historic Casco Viejo with great decor and top-notch service. The entire inner patio is filled with tropical plants to create a special oasis and there are only 8 rooms available to keep the setting intimate. The best part is having a rooftop jacuzzi where you can enjoy gorgeous views and a craft cocktail. Be sure to also dine at their restaurant Kaandela whether you’re staying here or not for flavourful Latin-inspired dishes.

American Trade Hotel | BOOK NOW

Location: Casco Viejo, Panama City

The American Trade Hotel is one of the most stylish places to stay in the historic Casco Viejo neighborhood of Panama City. Besides the eye-catching lobby and rooms, the hotel has an array of amenities to keep you entertained. Grab a premium cup of coffee at the attached Unido Cafe, enjoy fine dining at the lobby level restaurant, listen to an amazing jazz concert at Danilo’s Jazz Club, and take a dip in the rooftop pool after a hot day of exploring Casco Viejo.

La Concordia | BOOK NOW

Location: Casco Viejo, Panama City

La Concordia offers elegant charm right in the middle of the historic district. Many rooms have their own private balconies and the building also has a beautiful rooftop terrace perfect for viewing the sunset.

Villa Noelia | BOOK NOW

Location: Isla Saboga, Pearl Islands

Saboga is an undeveloped island off the coast of Panama City. It is a nature lover’s paradise, with numerous totally deserted beaches and a tropical jungle. Villa Noelia is a gorgeous home with several rooms available for rent. The best part of staying here is the stunning views, the swimming pool, and its steps from one of the best beaches. You can also walk over to the sister property, Saboga Lodge, for cool vibes and delicious food at the restaurant.

Sonny Island Resort | BOOK NOW

Location: Isla Bolaños, Pearl Islands

Sonny Island is a fabulous resort and the only one located on the island. They have top-notch modern & stylish amenities with several cabins you can rent for the night. Breakfast and lunch are also included in the nightly rate. If you don’t have time to stay overnight, you can also book a day trip HERE.

Saboga Lodge | BOOK NOW

Location: Isla Saboga, Pearl Islands

Within the Pearl Islands sits Saboga Lodge, a bohemian chic oasis immersed in the middle of the forest. While here you can take a splash in the pool, practice yoga on the deck (mats included), and walk to one of the several beaches on the island. They also have a staff member available that can assist you with booking tours, food, or any special requests. 

La Semilla Ecolodge |  BOOK NOW

Location: Cerro Azul

La Semilla is only 1-hour from Panama City, exclusively set within beautiful private gardens surrounded by colorful flora and fauna. This Ecolodge is for people looking to experience nature with the amenities of a boutique hotel. On-site amenities feature a gourmet restaurant, full bar, open-air terrace with a retractable roof, jacuzzi, billiards, and movie lounge. Coming in 2021 – swimming pool, steam room, spa, and more! 

Punta Malibu | BOOK NOW

Location: Playa Malibu, Panama

Sky Ocean Pads offers a luxurious private getaway right on the beach with unobstructed ocean views. It’s located on Playa Malibu, approximately 1.5 hours from Panama City. 

Sansara Resort | BOOK NOW

Location: Cambutal

In the remote town of Cambutal sits a luxury surf & yoga retreat waiting to be discovered. Sansara Resort features a spa, yoga & surf classes, private beach, and an oceanfront saltwater pool. The restaurant and bar at the hotel is world class serving only the best farm to table local ingredients, an array of fresh juices, smoothies, and incredible cocktails.

Villa Caprichosa | BOOK NOW

Location: Isla Taboga

Villa Caprichosa looks like it’s straight from a fairy tale. It is located on Taboga Island, which is only 30-minutes from Panama City by ferry. The property was constructed by internationally renowned designer Diane Burn and took over seven years to build. With all of the intricate details, you would never guess it was made entirely out of concrete. It has been operating as a luxurious bed and breakfast (often getting a 10/10 rating from guests on on the island and now has the addition of offering visitors an incredible gourmet dinner.

El Sitio Lighthouse | BOOK NOW

Location: Playa Venao

Staying in a lighthouse is one of the most unique accommodation options. The lighthouse apartment features a spectacular 360º lookout of the bay. It’s equipped with a kitchenette, living room, bedroom, and bathroom. 

Camino del Sol | BOOK NOW

Location: Los Duarte

Camino del Sol is an impressive hideaway near the popular surfing destination of Playa Morillo. According to guests, “Sebastian was an incredible host and has created a little paradise on the Pacific coast, what an incredible place. Look forward to coming back here for longer next time.” Your experience at Camino del Sol includes an amazing breakfast prepared daily for you by Sebastian and an onsite restaurant for your other meals. The highlight of the property is definitely the infinity pool with a view of the surrounding hills and ocean.

Villa Coco | BOOK NOW

Location: Santa Catalina

Villa Coco is a beautiful boutique hotel in Santa Catalina, one of the top surf spots in Panama. The carefully designed cabins provide an atmosphere of tranquility where you can relax on the private terraces and in one of the relaxing hammocks or enjoying a refreshing drink from the bar. The restaurant “Ai Mamita” offers fresh & creative seafood dishes.

Bambuda Castle | BOOK NOW

Location: Boquete

Ever wanted to stay in a castle? Bambuda Castle is an affordable hotel & hostel in Boquete, Panama. The property features a pool, jacuzzi, and an outdoor rock climbing wall! According to guests, “A truly unique experience, a must do again. Food was excellent and prepared by a chef on site from Chile with a 10+ rating for presentation. The pool and hot tub was great and the grounds around the Castle was amazing. View from outside sitting area was truly spectacular.” The hotel also offers reasonably priced tours to Boquete’s most amazing outdoor experiences.

Golden Frog Inn | BOOK NOW

Location: El Valle de Antón

The Golden Frog Inn is a lush mountain getaway located in El Valle de Anton. The pool is surrounded by colorful tropical plants and a stunning backdrop for a photo. A delicious breakfast is included in the nightly rate. 

Sand Dollar Villa | BOOK NOW

Location: Boca Chica, Chiriqui

Sand Dollar Villa is a beautiful, very private retreat boasting panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second-largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach or relax at your private pool. 

Playa Escondida | BOOK NOW

Location: Maria Chiquita, Colón

Playa Escondida is one of the best-kept secrets in Panama. This new luxury development is located in Maria Chiquita, on the Caribbean side only 1-hour from Panama City. The water here is crystal clear with white sand and you have several swimming pools you can enjoy on the property. It’s one of the best places to enjoy an easy and beautiful escape from the city. 

Experience Panama


I'm Joey, a guy from Louisville, Kentucky that packed up and studied abroad in Panamá at the age of 20 and haven't moved back since. What started as a semester trip to Panamá has turned into 10+ years of living in Latin America and becoming a full-time travel blogger. I now rotate between living in Panama City, Bogotá, and Lima. Follow me on Instagram @joeybonura for more updates on my life abroad!

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