Panamanians always enjoy a good party! The nightlife here offers a little bit of something for everyone, from underground lairs to chic overpriced nightclubs with Panama’s “yeyecito” crowd. Most of the spots on this list are located in Casco Viejo, which in recent years has become the new epicenter of Panama City nightlife (so stay in this neighborhood if you like to party). From Sunday – Wednesday bars close at 3 am and Thursday, Friday, and Saturday bars close at 4 am. There are a few secret spots that stay open later but you’ll have to discover those for yourself 🙂

Here are the top 10 places you have to visit to get the best experience out of Panama’s nightlife.



Stringed lights, good DJ, skyline view, and trendy Panamanians and foreigners always create the perfect party atmosphere at Tantalo’s Rooftop. On Tuesday’s they have Artes Martes where they have a live artistic performance, Wednesday is Latin Night, Thursday is Ladies Night, and on Friday, Saturday, & Sunday you’ll find a trendy crowd dancing to the latest DJ mixes.

Casa Jaguar

Casa Jaguar starts as a restaurant but once the clock strikes midnight, this place gets wild! The best thing about Casa Jaguar is that it has two ambiances: a large indoor area that places a mix of music and an outdoor patio with electronic music.

Chupitos 507

Chuptios 507 is Panama City’s first shot bar features over 70 creative shots ranging from fire, beer bongs, and an infamous shot incorporating a special toy. Most shots are $5 but you can also pay $20 for open shots all night so it’s a fun spot to pregame at before heading to one of the nearby nightclubs. Be sure to also stop by their ladies night every Thursday where girls drink for free from 9:30 pm to 11:30 pm.

Gatto Blanco

The Gatto Blanco rooftop is located next to Tantalo, but has a much more bohemian vibe. They typically have a local DJ playing laid-back electronic music and it offers a lovely view of the glowing Panama City skyline.


El Sotano / El Apartamento

There’s no place like home, right? El Sotano (The Basement) and El Apartamento (The Apartment) has transformed a giant yellow house in Bella Vista into a bar and event venue. You can usually find live rock music on the first floor or head up to El Apartamento, which literally looks like an apartment, to listen to chill indie jams and enjoy a few drinks.

Moloko +

Moloko has quietly become one of Panama City’s favorite underground lairs for late night electronic music. The entrance is through a sketchy back alley in Casco Viejo after midnight through a nondescript black door with a red lightbulb overhead.

Piña Calavera

Piña Calavera recently moved to a new spot in the transitioning Avenida B area of Casco Viejo. This is one of the few spots in Panama City where you can enjoy live music from local talent.

La Tana

La Tana just opened in Casco Viejo and is the current hotspot locals are flocking to for a lush club experience. They typically play a mix of reggaeton, electronic, and current top 40 music. On Fridays, they typically have free shots for ladies from 10 pm to 11 pm.

Villa Agustina

Villa Agustina is one of the oldest bars that is still around in Casco Viejo. The ambiance is bohemian and one of the few places you will fit in wearing shorts. They typically play reggae, hip-hop, and reggaeton.

Coyo Taco

It may sound weird to say that you’re going to a taco place to party, but the second floor of Coyo Taco is a great spot to party on the weekend. They also bring in a number of big name international DJs to play.


So that’s my top 10 list of nightspots to visit before you leave Panama. If you want to be steps away from the nightlife I recommend staying in Casco Viejo! Besides being able to walk home from the bar you are in the heart of the city’s cultural and dining scene.


Casco Hotels


Luna’s Castle ($): Luna’s Castle is located at the entrance of Casco Viejo, so you’re surrounded by Panama City’s top bars and restaurants, and you have the city’s coolest underground bar located downstairs. Also one of the most favorite spots to stay for backpackers, so it’s great place to meet people. 

Magnolia Inn ($): The Magnolia Inn a luxury hostel and hotel located in the heart of Casco Viejo, and it’s best for if you want an affordable and nice hostel to stay in Casco Viejo without the party atmosphere that Luna’s Castle has. Each bed even has its own plug and wall lamp.

Tantalo ($$): Tantalo is one of the hippest boutique hotels in Casco Viejo with uniquely designed rooms and home to Panama City’s hottest rooftop bar.

Villa Palma Boutique Hotel ($$$): The Villa Palma Boutique Hotel is elegantly decorated and one of the best values for luxury accommodation in Casco Viejo. It’s also located away from any noisy establishments so you can actually get some sleep if that’s what you’re after.

American Trade Hotel ($$$$): Swimming pools are hard to come by in this historic sector of the city, so it’s exciting when a hotel offers this amenity. The American Trade Hotel is one of the few spots in Casco with a pool so you can spend the day meandering through the charming streets and then relax in the pool before a fun night out – plus the hotel is gorgeous.


I'm Joey, a guy from Louisville, Kentucky that packed up and studied abroad in Panamá at the age of 20 and haven't moved back since. What started as a semester trip to Panamá has turned into 7+ years of living in Latin America and becoming a full-time travel blogger. Follow me on Instagram @joeybonura for more updates on my life abroad!


  1. Great article Joey,

    Indeed 10 of the best places to be in Panama! 😀
    And one great option to discover 5 of them while meeting new people from around the world is to join the Panama BAR CRAWL!!

  2. Relic is definitely one of the best here, casco antiguo has been the favorite night spot at weekends in the city but what about la Buat and altabar they re really good as well

  3. I love your BLOG man! I was born and raised in Panama and lived there for 20 years before I moved. I now live in Florida, but I haven't been back home since the treaty was signed over to Panama…

    I sure do miss it!

    You blog does the trick for me and I feel that I'm right at home…


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