Panamanians always enjoy a good party! The nightlife here offers a little bit of something for everyone, from underground lairs to chic overpriced nightclubs with Panama’s “yeyecito” crowd. Most of the spots on this list are located in Casco Viejo, which in recent years has become the new epicenter of Panama City nightlife (so stay in this neighborhood if you like to party). From Sunday – Wednesday bars close at 3 am and Thursday, Friday, and Saturday bars close at 4 am. There are a few secret spots that stay open later but you’ll have to discover those for yourself 🙂

Here are the top 10 places you have to visit to get the best experience out of Panama’s nightlife.



Stringed lights, good DJ, skyline view, and trendy Panamanians and foreigners always create the perfect party atmosphere at Tantalo’s Rooftop. On Tuesday’s they have Artes Martes where they have a live artistic performance, Wednesday is Latin Night, Thursday is Ladies Night, and on Friday, Saturday, & Sunday you’ll find a trendy crowd dancing to the latest DJ mixes.


Casa Jaguar

Casa Jaguar starts as a restaurant but once the clock strikes midnight, this place gets wild! The best thing about Casa Jaguar is that it has two ambiances: a large indoor area that places a mix of music and an outdoor patio with electronic music.


Chupitos 507

Panama City’s first shot bar features over 70 creative shots ranging from fire, beer bongs, and an infamous shot incorporating a special toy. Most shots are $5 but you can also pay $20 for open shots all night so it’s a fun spot to pregame at before heading to one of the nearby nightclubs. Be sure to also stop by their ladies night every Thursday where girls drink for free from 9:30 pm to 11:30 pm.

🔥 A ver, ¿Quienes están Act? #Toy #Chupitos507 😏

A post shared by Chupitos507 (@chupitos507) on


Red Lion Beach Club

Red Lion Beach Club is located on Playa Veracruz (25 min from the city) and typically throws a party on Saturday nights. It has also become a favorite spot for after hours once the bars in the city close.


Gatto Blanco

The Gatto Blanco rooftop is located next to Tantalo, but has a much more bohemian vibe. They typically have a local DJ playing laid-back electronic music and it offers a lovely view of the glowing Panama City skyline.



El Sotano / El Apartamento

There’s no place like home, right? El Sotano (The Basement) and El Apartamento (The Apartment) has transformed a giant yellow house in Bella Vista into a bar and event venue. You can usually find live rock music on the first floor or head up to El Apartamento, which literally looks like an apartment, to listen to chill indie jams and enjoy a few drinks.


Moloko +

Moloko has quietly become one of Panama City’s favorite underground lairs for late night electronic music. The entrance is through a sketchy back alley in Casco Viejo after midnight through a nondescript black door with a red lightbulb overhead.


Piña Calavera 

Piña Calavera recently moved to a new spot in the transitioning Avenida B area of Casco Viejo. This is one of the few spots in Panama City where you can enjoy live music from local talent.


La Tana

La Tana just opened in Casco Viejo and is the current hotspot locals are flocking to for a lush club experience. They typically play a mix of reggaeton, electronic, and current top 40 music. On Fridays, they typically have free shots for ladies from 10 pm to 11 pm.


Villa Agustina

Villa Agustina is one of the oldest bars that is still around in Casco Viejo. The ambiance is bohemian and one of the few places you will fit in wearing shorts. They typically play reggae, hip-hop, and reggaeton.

Calentando para la batalla!! Lleguen!

A post shared by Villa Agustina (@villaagustina) on


So that’s my top 10 list of nightspots to visit before you leave Panama. There are lot more places that I wish I could add to the list but I think those give you the best mix of everything. Leave a comment below with your favorite bars and clubs in Panama City!


I'm from Louisville, Kentucky and moved to Panama in 2011 to finish a degree in International Business. I enjoyed the hot tropical weather and the lifestyle on offer in Panama City so much that I decided to make it my permanent residence. Follow @JoeyBonura on Twitter and Instagram for more updates on my life in Panama.


  1. Great article Joey,

    Indeed 10 of the best places to be in Panama! 😀
    And one great option to discover 5 of them while meeting new people from around the world is to join the Panama BAR CRAWL!!

  2. Relic is definitely one of the best here, casco antiguo has been the favorite night spot at weekends in the city but what about la Buat and altabar they re really good as well

  3. I love your BLOG man! I was born and raised in Panama and lived there for 20 years before I moved. I now live in Florida, but I haven't been back home since the treaty was signed over to Panama…

    I sure do miss it!

    You blog does the trick for me and I feel that I'm right at home…


Leave a Reply